[EMERGING]Emerging
Review of actinobacteria in indoor environments and reported respiratory effects
A review of indoor actinobacteria reported their occurrence in moisture-damaged buildings, methods for measuring them, and documented respiratory effects including allergic alveolitis.
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This library reports what studies found. An entry describes a study's design, its findings in its own terms, and its limits. Nothing here is a claim about what a Sage Co. home does, delivers, or prevents.
Last reviewed August 30, 2026.
What they studied
- A literature review covering actinobacterial biology, occurrence in indoor environments, and exposure assessment methods.
- Reported health effects associated with actinobacterial exposure in indoor and occupational settings.
- Measurements taken before, during, and after remediation of moisture-damaged buildings.
What they found
- The author reported that actinobacteria are immunoactive organisms associated with allergic alveolitis in the reviewed literature.
- Actinobacterial concentrations were reported to rise during remediation activity in moisture-damaged buildings.
- Exposure assessment methods were reported to vary widely, complicating comparison across studies.
What this study does not establish
- A narrative review; it pools heterogeneous methods and does not quantify pooled risk.
- Most reported health effects come from occupational settings rather than residences.
- No dose-response threshold for residential exposure is established.
- This entry reports the study. It is not a statement about any building Sage Co. designs or constructs.
Source
Rintala H (2011). Actinobacteria in indoor environments: exposures and respiratory health effects. Frontiers in Bioscience (Scholar Edition) 3(4):1273–1284.
actinomycetesbacteriaremediationreview
Elsewhere under Moisture & Mold
- Meta-analyses of respiratory health outcomes reported in damp or moldy homes
- Review of epidemiologic evidence on dampness, mold, and dampness-related agents
- Bacteria, molds, and toxins measured in water-damaged building materials
- Actinomycetes and non-tuberculous mycobacteria measured against respiratory findings in a water-damaged office building
- Culture and molecular methods compared for actinobacteria on water-damaged building material
- Inflammatory response in mice after instillation of Streptomyces spores from a moldy building
- Co-occurrence of bacterial and fungal secondary metabolites measured in moisture-damaged homes
- Chaetomium globosum prevalence in surveyed water-damaged buildings and metabolite production on building materials
- Metabolites of Wallemia sebi measured at water activity below common mold-growth thresholds
- Associations between fungal species and specific water-damaged building materials
- Systematic review of fungal exposure and hypersensitivity pneumonitis
- Review of Stachybotrys chartarum, trichothecene mycotoxins, and damp building–related illness
- Immune response measured after single versus repeated Stachybotrys lung exposures in mice
- Nasal and olfactory effects of satratoxin G measured in rhesus monkeys
- Olfactory neuron loss and inflammation measured in mice after intranasal satratoxin G
- Lung inflammation measured in mice exposed to Aspergillus versicolor spores from a moisture-damaged building
- Inflammatory gene expression measured in macrophages exposed to toxins from damp-building fungi
- Lung responses measured in mice exposed to purified toxins from building-isolated Penicillium species
- Human brain cell responses measured at satratoxin concentrations reported from water-damaged buildings
- Time-series and clinical-trial data reported on illness in water-damaged building occupants
- Review of proposed injury mechanisms from exposure to water-damaged buildings
- Neuropsychological and electrocortical measures compared between mold-exposed subjects and controls
