Research — Indoor Air Quality

Entries filed under this domain. Each reports one study.

How to read this

This library reports what studies found. An entry describes a study's design, its findings in its own terms, and its limits. Nothing here is a claim about what a Sage Co. home does, delivers, or prevents.

Read the Indoor Air Quality domain page

[EMERGING]Emerging
Cognitive test scores measured against CO2, ventilation, and VOC levels in an office setting
In a controlled office-simulation experiment, participants' scores on a cognitive-function test instrument were reported to differ across ventilation, CO2, and VOC conditions.
Allen JG, MacNaughton P, Satish U, Santanam S, Vallarino J, Spengler JD, 2016 · Environmental Health Perspectives 124(6):805–812
[ESTABLISHED]Established
Toxicological review of microbial volatile organic compounds in moisture-damaged buildings
A toxicological review catalogued the volatile compounds produced by indoor fungi and bacteria and summarized the exposure and toxicity data available for the most commonly detected ones.
Korpi A, Järnberg J, Pasanen A-L, 2009 · Critical Reviews in Toxicology 39(2):139–193
[EMERGING]Emerging
Acute responses measured in a controlled human exposure to 1-octen-3-ol
In a double-blind controlled exposure, volunteers exposed to the fungal volatile 1-octen-3-ol for two hours showed measured nasal inflammatory markers and reported symptoms.
Wålinder R, Ernstgård L, Norbäck D, Wieslander G, Johanson G, 2008 · Toxicology Letters 181(3):141–147
[EMERGING]Emerging
Dopamine handling and neurodegeneration measured in model systems exposed to 1-octen-3-ol
In fruit fly and human cell models, the fungal volatile 1-octen-3-ol was reported to disrupt dopamine transport and produce dopaminergic neuron degeneration.
Inamdar AA, Hossain MM, Bernstein AI, Miller GW, Richardson JR, Bennett JW, 2013 · Proceedings of the National Academy of Sciences USA 110(48):19561–19566
[EMERGING]Emerging
Classroom microbial VOC measurements compared against reported respiratory symptoms in pupils
Measured microbial volatile compounds in Swedish classrooms were reported in association with respiratory symptoms and diagnosed asthma among the pupils studied.
Kim JL, Elfman L, Mi Y, Wieslander G, Smedje G, Norbäck D, 2007 · Indoor Air 17(2):153–163
[EMERGING]Emerging
Measured dwelling microbial VOCs compared against sick building syndrome reports in three cities
A multi-country residential study reported associations between measured microbial volatile compounds in homes and occupant reports of mucosal and general symptoms.
Sahlberg B, Gunnbjörnsdottir M, Soon A, Jogi R, Gislason T, Wieslander G, Janson C, Norbäck D, 2013 · Science of the Total Environment 444:433–440
[EMERGING]Emerging
Review asking whether some fungal volatile compounds meet the definition of mycotoxins
A review argued that certain volatile fungal metabolites have toxicological properties comparable to particulate mycotoxins and proposed treating them as a distinct class.
Bennett JW, Inamdar AA, 2015 · Toxins (Basel) 7(9):3785–3804
[EMERGING]Emerging
Airborne gram-negative bacteria and endotoxin measured across office buildings with differing symptom rates
A survey of office buildings reported substantially higher airborne endotoxin concentrations in buildings where occupants reported more symptoms.
Teeuw KB, Vandenbroucke-Grauls CMJE, Verhoef J, 1994 · Archives of Internal Medicine 154(20):2339–2345
[EMERGING]Emerging
Proinflammatory mediators measured in cell lines exposed to indoor bacteria and fungal spores
In mouse and human cell lines, a gram-negative bacterium isolated indoors produced stronger inflammatory mediator responses than the indoor fungi tested alongside it.
Huttunen K, Hyvärinen A, Nevalainen A, Komulainen H, Hirvonen M-R, 2003 · Environmental Health Perspectives 111(1):85–92
[EMERGING]Emerging
Dust fungi and endotoxin measured against respiratory symptoms in a water-damaged office building
In a study of occupants of one water-damaged office building, both fungal and endotoxin measures in dust were reported in dose-response association with respiratory symptoms, with an interaction between them.
Park J-H, Cox-Ganser JM, Rao C, Kreiss K, 2006 · Indoor Air 16(3):192–203
[EMERGING]Emerging
Chemical marker analysis used to detect microbial colonization in water-damaged building materials
A method study reported that 3-hydroxy fatty acid markers of gram-negative bacteria remained detectable in building materials for weeks after water damage.
Szponar B, Larsson L, 2000 · Indoor Air 10(1):13–18
[EMERGING]Emerging
Endotoxin, ergosterol, muramic acid, and fungal DNA measured in school dust against rhinitis reports
In classroom dust, specific molecular species of endotoxin were reported in association with rhinitis while total endotoxin showed an inverse association.
Norbäck D, Hashim JH, Markowicz P, Cai G-H, Hashim Z, Ali F, Larsson L, 2016 · Science of the Total Environment 545–546:95–103
[EMERGING]Emerging
Airborne macrocyclic trichothecene mycotoxins measured in water-damaged indoor environments
Air sampling in water-damaged buildings detected macrocyclic trichothecene mycotoxins, with concentrations reported to rise during simulated occupant activity.
Brasel TL, Martin JM, Carriker CG, Wilson SC, Straus DC, 2005 · Applied and Environmental Microbiology 71(11):7376–7388
[EMERGING]Emerging
Satratoxin G and H measured in indoor air of a water-damaged dwelling
Mass-spectrometric analysis of air sampled in one water-damaged dwelling detected satratoxin G and satratoxin H at nanogram-per-cubic-meter concentrations.
Gottschalk C, Bauer J, Meyer K, 2008 · Mycopathologia 166(2):103–107
[EMERGING]Emerging
Mycotoxin survey of building material samples from water-damaged buildings
A survey of building material samples from water-damaged buildings reported that a majority tested positive for at least one mycotoxin.
Bloom E, Nyman E, Must A, Pehrson C, Larsson L, 2009 · Journal of Occupational and Environmental Hygiene 6(11):671–678
[EMERGING]Emerging
Systematic review of airborne mycotoxin exposure across environments and tasks
A systematic review of airborne mycotoxin studies reported that mycotoxins travel adsorbed to dust and fungal fragments, and that co-detection of multiple toxins was the common finding.
Marcelloni AM, Pigini D, Chiominto A, Gioffrè A, Paba E, 2024 · Annals of Work Exposures and Health 68(1):19–35

References

Building-science articles, agency guidance, and standards we read and work from under this domain. Pointers to the source, not reports of a finding.

Research — Indoor Air Quality

How to read this

Cognitive test scores measured against CO2, ventilation, and VOC levels in an office setting

Toxicological review of microbial volatile organic compounds in moisture-damaged buildings

Acute responses measured in a controlled human exposure to 1-octen-3-ol

Dopamine handling and neurodegeneration measured in model systems exposed to 1-octen-3-ol

Classroom microbial VOC measurements compared against reported respiratory symptoms in pupils

Measured dwelling microbial VOCs compared against sick building syndrome reports in three cities

Review asking whether some fungal volatile compounds meet the definition of mycotoxins

Airborne gram-negative bacteria and endotoxin measured across office buildings with differing symptom rates

Proinflammatory mediators measured in cell lines exposed to indoor bacteria and fungal spores

Dust fungi and endotoxin measured against respiratory symptoms in a water-damaged office building

Chemical marker analysis used to detect microbial colonization in water-damaged building materials

Endotoxin, ergosterol, muramic acid, and fungal DNA measured in school dust against rhinitis reports

Airborne macrocyclic trichothecene mycotoxins measured in water-damaged indoor environments

Satratoxin G and H measured in indoor air of a water-damaged dwelling

Mycotoxin survey of building material samples from water-damaged buildings

Systematic review of airborne mycotoxin exposure across environments and tasks

References